Dermatological and Cardiac Manifestations of Wegener's Disease

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Manuel Enrique Vadillo Flores
Miguel Ángel Sánchez Dorantes
María Erika Boza Medrano
María Fernanda Guijosa Ortega
Paola Daniela Guerrero Ramírez
Omar Alejandro Avila Hernández

Abstract

Wegener's disease, also known as Granulomatosis with Polyangiitis (GPA), is a rare autoimmune disorder that affects small- to medium-sized blood vessels, causing inflammation and damage to various organs. The disease commonly involves the respiratory tract, kidneys, and the skin. In terms of dermatological symptoms, patients may develop purpura, which are small red or purple spots on the skin caused by bleeding under the skin, or nodules or ulcers that may be painful or non-painful. These lesions can occur anywhere on the body but are often found on the lower legs. Vascular involvement can lead to necrotizing vasculitis, which can be life-threatening if not treated promptly. Early diagnosis and treatment with immunosuppressive therapy can help manage the symptoms and prevent organ damage.

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Manuel Enrique Vadillo Flores, Miguel Ángel Sánchez Dorantes, María Erika Boza Medrano, María Fernanda Guijosa Ortega, Paola Daniela Guerrero Ramírez, & Omar Alejandro Avila Hernández. (2023). Dermatological and Cardiac Manifestations of Wegener’s Disease. International Journal of Medical Science and Clinical Research Studies, 3(4), 644–647. https://doi.org/10.47191/ijmscrs/v3-i4-13
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